Cryptococcal meningitis
نویسنده
چکیده
© 2004 Blackwell Publishing Ltd the second most common cause of death in HIV infection after tuberculosis (French et al. 2002). Moreover, despite the availability of highly active antiretroviral therapy (HAART), it continues to pose diffi cult management questions in the industrialized world. Questions remain for physicians regarding the optimal combination of antifungal agents, duration of treatment, accurate indicators of response to therapy, management of raised intracranial pressure, and the role of adjunctive therapies such as corticosteroids or other anti-infl ammatory agents. REVIEW
منابع مشابه
Pitfalls Associated With the Use of Molecular Diagnostic Panels in the Diagnosis of Cryptococcal Meningitis
We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular diagnostic panel. Caution with such platforms in suspected cryptococcal meningitis is needed.
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OBJECTIVE Mycobacterium tuberculosis and Cryptococcus neoformans are major causes of meningitis in HIV-1-infected patients. Identifying differences in the inflammatory profiles of HIV-1-associated tuberculous meningitis (TBM) and cryptococcal meningitis may inform differences in immunopathogenic mechanisms in these diseases. In this study we compared the clinical and inflammatory features of HI...
متن کاملCryptococcal meningitis in an immunocompetent patient: a case report and review of the literatures
Cryptococcal meningitis is an opportunistic infection in immunosuppressed hosts with high morbidity and mortality. Once suffering from cryptococcal meningitis, immunocompetent patients are more likely to achieve poor outcome, because of the powerful immune response. Here we present a case of cryptococcal meningitis occurring in an immunocompetent host with no definite underlying diseases and no...
متن کاملAnti-GM-CSF autoantibodies in patients with cryptococcal meningitis.
Cryptococcal meningitis has been described in immunocompromised patients, as well as in those for whom no immune defect has been identified. GM-CSF regulates the function of phagocytes and pulmonary alveolar macrophages, critical elements in cryptococcal control. We performed clinical histories, immunological evaluation, and anticytokine autoantibody screening in four current patients with cryp...
متن کاملSpinal Cryptococcoma Mimicking Spinal Cord Tumor Complicated by Cryptococcal Meningitis in an Immunocompetent Patient
There are very few cases in the literature on spinal cryptococcomas occurring alone without cerebral involvement at onset. Although cases of cerebral cryptoccomas followed by arachnoiditis have been reported, cases of spinal cryptococcoma followed by cryptococcal meningitis are exceedingly rare. We present a patient with spinal cord cryptococcoma who subsequently developed cryptococcal meningit...
متن کاملCryptococcal meningitis complicating sarcoidosis
BACKGROUND Cryptococcal meningitis is an uncommon but severe complication of sarcoidosis. METHODS We present 2 patients with cryptococcal meningitis complicating sarcoidosis and compared findings with 38 cases reported in the literature. RESULTS When analyzing our patients and 38 cases reported in the literature, we found that median age of sarcoidosis patients with cryptococcal meningitis ...
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